This book is written to clarify some aspects of stem cell biology, their
characteristics, assessment of damage to cells during ex vivo manipulation and
also their role in a model of cancers. Topics covered includes: Regulators of
the Proliferation of Hematopoietic Stem and Progenitor Cells During
Hematopoietic Regeneration, Hematopoietic Stem Cell Niche, Hematopoietic Stem
Cells in Chronic Myeloid Leukemia.
This note covers the following
topics: Protein Structure and Function, The Flow of Information: DNA to Protein,
Ribosome, mRNA, and tRNA direct the Synthesis of Proteins, Gene Regulation, DNA
Packing and Organization, Cell Cycle and Division, Cell Signaling, Cell
Junctions, Cell Adhesion and ECM, Nervous System.
This note covers the
following topics: Precellular evolution, Oparin and Haldane hypothesis,
Precursors to purines, Origin of polymers, Conservation of Group 1 introns, RNA
as polymerase, RNA as nuclease and ligase, RNA genome, Genetic code and
David Fitch, Department of Biology, New York University
This note explains the following topics related to Cellular and nuclear
reprogramming: Inducing pluripotency, Stem cells in animal models of
regeneration, Small RNAs – their biogenesis, regulation and function in
embryonic stem cells.
T Rodolfa, Kyle A. Gurley, Alejandro Sanchez Alvarado, Joshua E. Babiarz, Robert
This note explains the following topics: Immunologic targeting
of the cancer stem cell, Immunological considerations for cell therapy using
human embryonic stem cell derivatives, Mouse models of graft-versus-host
disease, Prospects for ensuring acceptance of ES cell-derived tissues.
note explains the following topics: Hematopoietic
stem cell trafficking, Trafficking of hematopoietic stem cells during
embryogenesis and fetal development, Post-natal HSC migration to bone marrow,
Egress of bone marrow HSCs to the periphery and the neural stem cell
Author(s): Claire Magnon, Paul S. Frenette,
Ilias Kazanis, Justin Lathia, Lara Moss, Charles ffrench-Constant
This note explains the following topics: Epigenetic mechanisms controlling mesodermal specification, Imaging chromatin in
embryonic stem cells, Epigenetic silencing during early lineage commitment, The
chromatin signature of pluripotent cells, Stem cells, cancer, and epigenetics.