This note serves as a
description and critical assessment of the major issues and stages of developing
a pharmaceutical or biopharmaceutical. Topics covered include drug discovery,
preclinical development, clinical investigation, manufacturing and regulatory
issues considered for small and large molecules, and economic and financial
considerations of the drug development process.
Author(s): Prof. Charles Cooney, Stan
Finkelstein, MD, Dr. G. K. Raju and Prof. Anthony Sinskey
The purpose of the textbook is to
help the students of higher medical institutions of the 4th level of
accreditation to study general concepts of Pharmacology and properties of drugs
acting on different systems of the human body. This textbook has been prepared
in order to improve the students’ self-training for the lessons under the
conditions of implementation of the educational system of Bolonga.
Author(s): The
Ministry of Public Health Care of Ukraine
The guideline on Drug misuse sets out clear, evidence-based recommendations
for healthcare staff on how to work with people who misuse opioids to
significantly improve their treatment and care, and to deliver detoxification
safely and effectively.
Author(s): National Collaborating Centre for Mental Health
(UK)
Pharmacology
is a broad discipline encompassing every aspect of the study of drugs, including
their discovery and development and the testing of their action in the body.
This book aims to explain how scientists unravel the many different ways
medicines work in the body and how this information guides the hunt for drugs of
the future.
Author(s): US Department of Health and Human Services
This book gives an overview of all
the known anticoagulants that can be useful for studying different aspects of
the haemostatic system or as a starting point for new drug development. It is
also a valuable tool for clinicians providing a description of the mode of
action and management of therapy for anticoagulant drugs used in daily clinical
practice in different clinical settings, including direct oral anticoagulants
dabigatran, rivaroxaban, edoxaban and apixaban .
Pharmacology and Nutritional Intervention in the Treatment of Disease is
a book dealing with an important research field that has worldwide significance.
Its aim is to strengthen the research base of this field of investigation as it
yields knowledge that has important implications for biomedicine, public health
and biotechnology. The basic purpose of this book was to promote interaction and
discussion of problems of mutual interests among people in related fields
everywhere.
This note explains the
following topics: Principles of Pharmacology, Drug Absorption and Distribution,
Drug Elimination and Multiple Dosing, Clinical Pharmacokinetics, Drug
Metabolism, Pharmacogenomics, Drug Toxicity, Pharmacodynamics, Drugs Discovery
and Clinical Trials.
The authors of this book look from different
angles to hypertension, sharing their new knowledge and experience in the
direction of deep understanding and more clarification of the disease providing
an invaluable resource not only for clinicians, but also for all medical
sciences students and health providers.
This note serves as a
description and critical assessment of the major issues and stages of developing
a pharmaceutical or biopharmaceutical. Topics covered include drug discovery,
preclinical development, clinical investigation, manufacturing and regulatory
issues considered for small and large molecules, and economic and financial
considerations of the drug development process.
Author(s): Prof. Charles Cooney, Stan
Finkelstein, MD, Dr. G. K. Raju and Prof. Anthony Sinskey
This guide will help you understand the relationship between
drugs, the body, and behavior and allow you to better evaluate drug use and
abuse, including use by you and your loved ones. It will increase your awareness
of controversies in the drugs field and enable you to make better decisions,
backed by critical thinking, when you face personal or social issues concerning
the use of drugs in the future.
This book considers the basic principles of biopharmaceutics and
pharmacokinetics. It also illustrates clinical pharmacokinetic applications,
such as recirculatory models, common antimalarial drugs, and clinical
pharmacokinetic principles in critically ill patients, which are essential for
medical professionals.
In the fields of medicine, drug discovery is the
process by which new candidate medications are discovered. This book
demonstrates that various expertise are essential for drug discovery including
synthetic or natural drugs, clinical pharmacology, receptor identification, drug
metabolism, pharmacodynamic and pharmacokinetic research. The following 5
sections cover diverse chapter topics in drug discovery: Natural Products as
Sources of Leading Molecules in Drug Discovery; Oncology and Drug Discovery;
Receptors Involvement in Drug Discovery; Management and Development of Drugs
against Infectious Diseases; Advanced Methodology.
This book provides selected but
vital information on the sources, tools, technologies and regulations regarding
the current status of medicine development.
Natural products are a constant source of potentially active
compounds for the treatment of various disorders.Plant derived secondary
metabolites have been used by humans to treat acute infections, health disorders
and chronic illness for tens of thousands of years. Only during the last 100
years have natural products been largely replaced by synthetic drugs.Books on
drug discovery will play vital role in the new era of disease treatment using
natural products.