This note covers the following topics: red blood cells normal morphology, Red blood cells, abnormal RBC
Morphology, Red blood cells abnormal RBC Inclusions, Red blood cells hypochromic,
Microcytic anemias, Red blood cells DNA metabolism abnormalities and bone
marrow failure, Introduction to hemolytic anemias, Hemoglobinopathies, Extrinsic
defects causing hemolytic anemias, Intrinsic defects of the RBC membrane causing
hemolytic anemia, White blood cells and platelets normal morphology, Non
malignant leukocyte disorders, Acute leukemia, Mature lymphoid neoplasms,
Myeloproliferative neoplasms and myelodysplastic syndromes.
This note covers the following topics: red blood cells normal morphology, Red blood cells, abnormal RBC
Morphology, Red blood cells abnormal RBC Inclusions, Red blood cells hypochromic,
Microcytic anemias, Red blood cells DNA metabolism abnormalities and bone
marrow failure, Introduction to hemolytic anemias, Hemoglobinopathies, Extrinsic
defects causing hemolytic anemias, Intrinsic defects of the RBC membrane causing
hemolytic anemia, White blood cells and platelets normal morphology, Non
malignant leukocyte disorders, Acute leukemia, Mature lymphoid neoplasms,
Myeloproliferative neoplasms and myelodysplastic syndromes.
The
book has been divided into three sections. The first section includes chapters
describing the immunological and coagulation-assisting functions of red blood
cells and methods to measure their life span. The second section discusses the
role of platelets in inflammatory processes. The third section reviews
functional dose of RBC transfusions and transfusion practice in various clinical
settings.
The book, Inherited Hemoglobin
Disorders, describes the genetic defects of hemoglobins, disease complications,
and therapeutic strategies. This book has two distinct sections. The first theme
includes seven chapters devoted to the types of hemoglobinopathies, mutation
spectrum, diagnostic methods, and disease complications, and the second theme
includes three chapters focusing on various treatment strategies. Major topics
covered includes: Hemoglobinopathy Approach Diagnosis and Treatment Policy,
Thalassemia, Sickle Cell Disease, Acute Splenic Sequestration Crisis, Sickle
Cell Disease.
The lecture note is intended for use by
laboratory technologist both during their training and in their work places.
There are study questions at the end of each chapter for the reader to evaluate his
understanding of the contents. In addition, important terms are defined in the
glossary section at the end of the text.
Author(s): Yared Alemu,
Alemayehu Atomsa and Zewdneh Sahlemariam