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This section contains free e-books and guides on Structural Biology, some of the resources in this section can be viewed online and some of them can be downloaded.

Structural Biology Books
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Structural Biology Reading

Online | NA Pages | English
This note covers the following topics: Basic Quantum Mechanics, UV absorption, Fluorescence, Circular Dichroism, IR/Raman, Intro Proteins, NMR, Solid State NMR, Single molecule, Protein-DNA Interactions, Calorimitry, X-ray, Electron Microscopy, Mass Spectrometry.

 
Biochemistry and Structural Biology

Online | NA Pages | English
This note covers the following topics: Structural Biology and Amino acids, History of Macromolecular Crystallography, Amino acid Chirality, Non-covalent interactions and Ramachandran Map, Secondary structures; Introduction to Protein , Alpha-domain proteins I: Coiled coils and four-helix bundle, ROP protein design, Alpha-domain proteins II: Large alpha-helical domain and globin fold, Alpha or Beta-domain proteins, Beta-domain proteins.

 
Workshop In Computational Structural Biology

Online | NA Pages | English
This note explores the concepts and algorithms that enable computational modeling of biological molecules, in both theory and practice. Topics covered includes: The basics of protein structure, Rosetta and structural modeling, Optimization techniques, Analysis of protein structures and assessment of model quality, Full atom refinement and side chain modeling, Hands-on: Side chain modeling, Homology modelin, Protein-protein docking.

 
Structural Biology Introduction

PDF | 82 Pages | English
This note aims to provide the knowledge of the basic protein molecular architecture and then to connect it to the basic cellular processes like enzymatic activity, transport and membrane functions.

 
Mathematical Techniques In Structural Biology

PDF | 86 Pages | English
These are notes about using mathematics to study the molecular structure of molecules, especially long organic molecules like DNA and proteins. Topics covered includes: Molecular Genetics: DNA, Proteins, Frames and moving frames, Orthogonal transformations and Rotations, Torsion angles and pdb files, X-ray Crystallography, Lattices, and Fourier Series, Nuclear Magnetic Resonance and distance geometry, Protein Folding.

 
Diffraction Techniques in Structural Biology

Online | NA Pages | English
This book combines a general overview of diffraction methods with a step-by-step description of the process of a single-crystal X-ray structure determination experiment, from chemical synthesis or expression to phasing and refinement, analysis and quality control . Topics covered includes: Major techniques in structural biology, X-ray fiber diffraction, Electron diffraction, Electron microscopy, Neutron diffraction, Nuclear magnetic resonance spectroscopy, Single crystal X-ray crystallography.

 
Protein Structure

Online | 396 Pages | English
The aim of this book is that a non expert can gain some appreciation for the intricacies involved, and in the current state of affairs. The expert meanwhile, can gain a deeper understanding of the topic.

 
Structural Biology Principles And Practices

Online | NA Pages | English
This note explains all the basic concepts related to structural biology.

 
Structural biology Protein Crystallography

Online | NA Pages | English
This note covers the following topics: Principles of protein structure, Hemoglobin, Platelet adhesion to collagen and Blood clotting.

 
Protein Structure and Function

Online | NA Pages | English
This note explains the following topics: Taxonomy : Primary and Secondary Structure, Motifs and Supersecondary Structure, Tertiary Structure and Fold Types, Forces that Determine Protein Structure, Mechanisms of Protein Folding, Multiscale Modeling of Electrostatics.

 
Principles of protein structure PDF Slides 56P

PDF | 56 Pages | English
This note explains the fundamentals of protein structure and the basics of molecular mechanics and dynamics.

 
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