This resource from the Scripps Center for Metabolomics
introduces the fundamental concepts of mass spectrometry (MS), so it is very
good for beginners. It includes the most essential facts about MS that concern
the principles of ionization, mass analyzers, and detectors, as well as
information on the vacuum system required for MS analysis. The note gives
foundational knowledge of how MS works: from the generation of ions from a
sample to the separation process and on to detection. Suitable for practitioners
who are just beginning a career in analytical chemistry or metabolomics, it
provides an easily accessible introduction to the technology and applications in
the analysis of complex molecular systems.
This guide is designed to introduce young students
aged between 6 and 14 to the field of mass spectrometry in a highly interactive
and hands-on laboratory experience. It describes the basic principles of the
technique in a way that is fun and accessible for children. It can be adapted in
modules to accomodate various age groups, providing an educational approach to
an introduction to the field of mass spectrometry. This resource sparks young
minds toward exploration of scientific concepts, especially in chemistry and
biology, and encourages curiosity about the world of molecular analysis.
This note presents
an overview of mass spectrometry at an advanced level with specific emphasis on
its utility in chemistry and biochemistry. Fundamental concepts include
ionization, mass analyzers, and dissociation of ions, as well as more advanced
topics like ion mobility and fragmentation. The qualitative and quantitative
analysis using mass spectrometry and the practical applications in various
fields are also considered. This note is designed for advanced students and
professionals aiming to gain insights into the role of mass spectrometry as an
analytical tool, both in theory and practice.