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Mass Spectrometry Scripps
This resource from the Scripps Center for Metabolomics introduces the fundamental concepts of mass spectrometry (MS), so it is very good for beginners. It includes the most essential facts about MS that concern the principles of ionization, mass analyzers, and detectors, as well as information on the vacuum system required for MS analysis. The note gives foundational knowledge of how MS works: from the generation of ions from a sample to the separation process and on to detection. Suitable for practitioners who are just beginning a career in analytical chemistry or metabolomics, it provides an easily accessible introduction to the technology and applications in the analysis of complex molecular systems.
Author(s): Scripps Center for Metabolomics
NA Pages 
This is a comprehensive note on X-ray spectroscopy techniques, aimed at detailing their applications in different fields, with an emphasis on the special applications in nanoparticles and molecular mechanisms. It begins with the introduction of XRF processes and techniques followed by high-resolution X-ray spectroscopy using compound semiconductor detectors and digital pulse processing systems. It also includes analytic applications of X-ray techniques, including dispersive X-ray spectroscopy as well as quantification in X-ray fluorescence spectrometry. In addition, it approaches specialized uses such as time-resolved X-ray absorption spectroscopy in the study of metalloproteins and the application of soft X-rays in astrochemistry. The note concludes discussing nanoscale chemical analysis that highlights energy dispersive X-ray spectroscopy (EDX) and transmission electron microscopy (TEM) with relevance to the characterization of interfaces and materials on the nanoscale.
Author(s): Shatendra K. Sharma
290 Pages
Principles and Applications of Mass Spectrometry
This note presents an overview of mass spectrometry at an advanced level with specific emphasis on its utility in chemistry and biochemistry. Fundamental concepts include ionization, mass analyzers, and dissociation of ions, as well as more advanced topics like ion mobility and fragmentation. The qualitative and quantitative analysis using mass spectrometry and the practical applications in various fields are also considered. This note is designed for advanced students and professionals aiming to gain insights into the role of mass spectrometry as an analytical tool, both in theory and practice.
Author(s): Derek J. Wilson
37 Pages