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Principles and Practice of Drug Development

This note serves as a description and critical assessment of the major issues and stages of developing a pharmaceutical or biopharmaceutical. Topics covered include drug discovery, preclinical development, clinical investigation, manufacturing and regulatory issues considered for small and large molecules, and economic and financial considerations of the drug development process.

Author(s): Prof. Charles Cooney, Stan Finkelstein, MD, Dr. G. K. Raju and Prof. Anthony Sinskey

NA Pages

This book is a fruit of a collaborative work from several international scientists. It will be a useful resource for researchers, students, and clinicians. Each individual chapter could serve as a prescribed reading for postgraduate students and clinicians specializing in and practicing clinical pharmacology and toxicology, pharmacotherapy and pharmacotherapeutics, pharmacovigilance, and toxicovigilance, as well as those involved in clinical research, drug discovery, and development.

Author(s): Ntambwe Malangu

NA Pages

Topics on Drug Metabolism

This book presents some in-depth reviews of selected topics in drug metabolism. Topics covered includes: Oral Absorption, Intestinal Metabolism and Human Oral Bioavailability, Pharmacogenetics and Metabolism, Altered Drug Metabolism and Transport in Pathophysiological Conditions, Anticancer Drug Metabolism: Chemotherapy Resistance and New Therapeutic Approaches, Transcription Factors Potentially Involved in Regulation of Cytochrome P450 Gene Expression, Electrochemical Methods for the In Vitro Assessment of Drug Metabolism, Pharmacogenomic Technology for Personalized Medicine.

Author(s): James Paxton

NA Pages

Recent Advances in Novel Drug Carrier Systems

This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. Topics covered includes: Hot-Melt Extrusion, Development and Investigation of Dry Powder Inhalers for Cystic Fibrosis, The Role of Carrier in Dry Powder Inhaler, Nanotechnology in Drug Delivery, Lipid Nanoparticulate Drug Delivery Systems, Niosomes as Carrier in Dermal Drug Delivery, Magnetic Nanoparticles, Targeted Nanoparticles for Cancer Therapy, Amphiphilic Cyclodextrins, Synthesis, Utilities and Application of Molecular Modeling in Their Design, Nanoparticles Toxicity and Their Routes of Exposures.

Author(s): Ali Demir Sezer

512 Pages

Respiratory Drug Guidelines

It is hoped that these guidelines will be used by all health care workers in their daily care of patients suffering from respiratory diseases. Topics covered includes: Drugs used in respiratory diseases, Inhalation drug delivery devices, Pulmonary function testing, Asthma, Chronic obstructive pulmonary disease, Cough, Upper respiratory tract Infections, Lower respiratory tract Infections, Suppurative lung disease, Interstitial lung disease, Pre- and post-operative Respiratory assessment.

Author(s): Ministry of Health, Government of Fiji Islands

111 Pages

Drug Discovery and Development From Molecules to Medicine

In the fields of medicine, drug discovery is the process by which new candidate medications are discovered. This book demonstrates that various expertise are essential for drug discovery including synthetic or natural drugs, clinical pharmacology, receptor identification, drug metabolism, pharmacodynamic and pharmacokinetic research. The following 5 sections cover diverse chapter topics in drug discovery: Natural Products as Sources of Leading Molecules in Drug Discovery; Oncology and Drug Discovery; Receptors Involvement in Drug Discovery; Management and Development of Drugs against Infectious Diseases; Advanced Methodology.

Author(s): Omboon Vallisuta and Suleiman Olimat

328 Pages

Pharmacology Lecture Notes

This lecture note on pharmacology is primarily a note for undergraduate health science students such as health officer, nursing, midwifery and laboratory technology students. The chapters open with a list of objectives to guide the reader, and most end with questions which challenge the reader�s understanding of the concepts covered with in the chapter. Most sections have an introduction that provides an overview of the material to be covered.

Author(s): Teferra Abula, Srinivasa A.Rao, Amare Mengistu, Solomomon Worku, Eshetu Legesse, Musie Aberra, Dawit, University of Gondar

211 Pages

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Principles and Practice of Drug Development

Principles and Practice of Drug Development

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