This book combines a
general overview of diffraction methods with a step-by-step description of the
process of a single-crystal X-ray structure determination experiment, from
chemical synthesis or expression to phasing and refinement, analysis and quality
control . Topics covered includes: Major techniques in structural biology, X-ray
fiber diffraction, Electron diffraction, Electron microscopy, Neutron
diffraction, Nuclear magnetic resonance spectroscopy, Single crystal X-ray
crystallography.
The aim of this book is that a non expert
can gain some appreciation for the intricacies involved, and in the current
state of affairs. The expert meanwhile, can gain a deeper understanding of the
topic.