Protein Structure

Biochemistry and Structural Biology

This note covers the following topics: Structural Biology and Amino acids, History of Macromolecular Crystallography, Amino acid Chirality, Non-covalent interactions and Ramachandran Map, Secondary structures; Introduction to Protein , Alpha-domain proteins I: Coiled coils and four-helix bundle, ROP protein design, Alpha-domain proteins II: Large alpha-helical domain and globin fold, Alpha or Beta-domain proteins, Beta-domain proteins.

Author(s): Dr. R. Sankararamakrishnan

NA Pages

Workshop In Computational Structural Biology

This note explores the concepts and algorithms that enable computational modeling of biological molecules, in both theory and practice. Topics covered includes: The basics of protein structure, Rosetta and structural modeling, Optimization techniques, Analysis of protein structures and assessment of model quality, Full atom refinement and side chain modeling, Hands-on: Side chain modeling, Homology modelin, Protein-protein docking.

Author(s): Prof. Ora Furman

NA Pages