This note covers the following topics: what is bioinformatics, Path to the bioinformatics, Scope of computational biology, The Central Dogma of Molecular Biology, Genomics, Proteomics, Killer application, Cells, Signaling Pathways Control gene activity, DNA the code of life and genetic information chromosomes.
Author(s): Yildiz Technical University
This page covers the following topics related to Bioinformatics : Text Mining Gene Selection to Understand Pathological Phenotype Using Biological Big Data, Single-Cell RNA Sequencing Procedures and Data Analysis, Computational Methods for Detecting Large-Scale Structural Rearrangements in Chromosomes, Machine Learning Approaches for Biomarker Discovery Using Gene Expression Data, Bayesian Inference of Gene Expression, Comprehensive Evaluation of Error-Correction Methodologies for Genome Sequencing Data, Plant Transcriptome Assembly: Review and Benchmarking,WeMine Aligned Pattern Clustering System for Biosequence Pattern Analysis, Rational Design of Profile Hidden Markov Models for Viral Classification and Discovery, Pattern Discovery and Disentanglement for Aligned Pattern Cluster Analysis and Protein Binding Complexes Detection.
Author(s): Nakaya Helder I., PhD.
The topics of notes in this site are as follows : Introduction to Bioinformatics, Sequence Alignment, Probabilistic Sequence Models , Gene Expression Analysis, Protein Structure Prediction.
Author(s): Burr Settles
The contents in this site includes the following topics : The complete course is comprised of three modules covering Foundations of Bioinformatics, Statistics in Bioinformatics, Systems Biology. These modules holds the following contents : Introduction to bioinformatics, Sequence Alignment and Database Searching, Structural Bioinformatics, Genome Informatics: High Throughput Sequencing Applications and Analytical Methods, Approaches to statistical estimation and testing, Statistical estimation and hypothesis testing, Analyses involving associations, Pearson correlation, t-test, and log odds ratios, Linear regression, Regression models, Introduction to graphical methods for multivariate data analysis, Clustering and principal component analysis, Introduction to systems biology, Epigenome data mining to understand disease predisposition, Computational clinical decision support systems, Application of systems biology to translational medicine.
Author(s): University of Michigan
This site hold 9 lectures on various topics related to Micorarray Methodology and Analysis such as Introduction to microarray technology, Image Processing for Pedestrians, Differential Expression, Microarray Normalization, Clustering and Classification, etc.
Author(s): M. Saleet Jafri, Program in Bioinformatics and Computational Biology, George Mason University
This PDF thesis A Bioinformatics Study of Human Transcriptional Regulation covers the following topics related to Bioinformatics : Biological background, DNA and chromosomes, Transcription, Transcriptional regulation, Medical aspects of transcriptional regulation, High-throughput technologies, DNA microarrays, Massively parallel sequencing, Biological knowledge sources, Annotations, Experimental data, Aims, Methods, Computational methods, Statistics Randomization, Local search, Analysis of high-throughput data, Experiment design, Expression analysis, ChIP-chip data analysis, ChIP-seq data analysis, Data storage and management, Results and discussion, Summary of results, Computational results, Biological results, Medical results, Additional results, Discussion.
Author(s): Adam Ameur
This note covers the following topics: Molecular Biology, Molecular Biology Information - DNA, Protein Sequence, Macromolecular Structure and Protein Structure Details, Gene Expression Datasets, New Paradigm for Scientific Computing, General Types of Informatics in Bioinformatics, Genome Sequence, Protein Sequence, Major Application: Designing Drugs, Finding Homologues, Genome Characterization.
Author(s): Mark Gerstein
This note explains the following topics: What is bioinformatics, Molecular biology primer, Biological words, Sequence assembly, Sequence alignment, Fast sequence alignment using FASTA and BLAST, Genome rearrangements, Motif finding, Phylogenetic trees and Gene expression analysis.
Author(s): Esa Pitkanen
This note explains the following topics: Modern approaches in Bioanalysis and Bioassays, Spectroscopic techniques: UV-Visible spectroscopy, Fluorescence spectroscopy, IR spectroscopy, CD spectroscopy, and Mass spectroscopy, Light Microscopy; Fluorescence microscopy, Atomic force microscope, Electron microscope, Scanning electron microscopy, Transmission Electron microsope, Application of microscope in analyzing biological samples.
Author(s): NPTEL
This note provides a hands-on approach to students in the topics of bioinformatics and proteomics. Topics covered includes: sequence analysis, microarray expression analysis, Bayesian methods, control theory, scale-free networks, and biotechnology applications.
Author(s): Prof. Gil Alterovitz, Prof. Manolis Kellis and Prof. Marco Ramoni
This book is intended to serve both as a textbook for short bioinformatics courses and as a base for a self teaching endeavor. It is divided in two parts: A. Bioinformatics Techniques and B. Case Studies. Each chapter of the first part addresses a specific problem in bioinformatics and consists of a theoretical part and of a detailed tutorial with practical applications of that theory using software freely available on the Internet.
Author(s): Chanchal Kumar
This book covers the following topics: biological basics needed in bioinformatics, Pairwise Alignment, Multiple Alignment, Phylogenetics, DNA, RNA, Transcription, Introns, Exons, and Splicing, Amino Acids.
Author(s): Sepp Hochreiter
This book covers the following topics: Machine Learning in Bioinformatics, Theoretical Background of Machine Learning, Support Vector Machines, Error Minimization and Model Selection, Neural Networks, Bayes Techniques, Feature Selection, Hidden Markov Models.
Author(s): Sepp Hochreiter
This note explains the relationship between biology, bioinformatics and computer science and shows the computational approaches used in bioinformatics.
Author(s): Marcel Turcotte
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Author(s): NA
This note covers the following topics: Biological preliminaries, Analysis of individual sequences, Pairwise sequence comparison, Algorithms for the comparison of two sequences, Variants of the dynamic programming algorithm, Practical Sections on Pairwise Alignments, Phylogenetic Trees and Multiple Alignments and Protein Structure.
Author(s): Max Planck Institute for Molecular Genetics
This note describes the computational challenges in structural biology and explains the computational methods for analysing and predicting macromolecular conformations and interactions and gives practice in programming techniques for structural bioinformatics.
Author(s): Graham Kemp and Per-Georg Nyholm
This note explains the basic bioinformatics concepts via a closed lab exercise and a programming project. Also discusses the implementation of these activities and some of the results/lessons we learned.
Author(s): Erica Eddy
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