Workshop In Computational Structural Biology

Workshop In Computational Structural Biology

This note explores the concepts and algorithms that enable computational modeling of biological molecules, in both theory and practice. Topics covered includes: The basics of protein structure, Rosetta and structural modeling, Optimization techniques, Analysis of protein structures and assessment of model quality, Full atom refinement and side chain modeling, Hands-on: Side chain modeling, Homology modelin, Protein-protein docking.

Author(s): Prof. Ora Furman

NA Pages

Diffraction Techniques in Structural Biology

This book combines a general overview of diffraction methods with a step-by-step description of the process of a single-crystal X-ray structure determination experiment, from chemical synthesis or expression to phasing and refinement, analysis and quality control . Topics covered includes: Major techniques in structural biology, X-ray fiber diffraction, Electron diffraction, Electron microscopy, Neutron diffraction, Nuclear magnetic resonance spectroscopy, Single crystal X-ray crystallography.

Author(s): Martin Egli

NA Pages