A Bioinformatics Study of Human Transcriptional Regulation
A Bioinformatics Study of Human Transcriptional Regulation
A Bioinformatics Study of Human Transcriptional Regulation
This
PDF thesis A Bioinformatics Study of Human Transcriptional Regulation covers the
following topics related to Bioinformatics : Biological
background, DNA and chromosomes, Transcription, Transcriptional regulation,
Medical aspects of transcriptional regulation, High-throughput technologies, DNA
microarrays, Massively parallel sequencing, Biological knowledge sources,
Annotations, Experimental data, Aims, Methods, Computational methods, Statistics
Randomization, Local search, Analysis of high-throughput data, Experiment
design, Expression analysis, ChIP-chip data analysis, ChIP-seq data analysis,
Data storage and management, Results and discussion, Summary of results,
Computational results, Biological results, Medical results, Additional results,
Discussion.
This note
covers the following topics: what is bioinformatics, Path to the bioinformatics, Scope of computational biology, The Central Dogma of
Molecular Biology, Genomics, Proteomics, Killer application, Cells, Signaling
Pathways Control gene activity, DNA the code of life and genetic information
chromosomes.
The topics of notes in this site are as
follows : Introduction to Bioinformatics, Sequence Alignment, Probabilistic
Sequence Models , Gene Expression Analysis, Protein Structure Prediction.
This
PDF thesis A Bioinformatics Study of Human Transcriptional Regulation covers the
following topics related to Bioinformatics : Biological
background, DNA and chromosomes, Transcription, Transcriptional regulation,
Medical aspects of transcriptional regulation, High-throughput technologies, DNA
microarrays, Massively parallel sequencing, Biological knowledge sources,
Annotations, Experimental data, Aims, Methods, Computational methods, Statistics
Randomization, Local search, Analysis of high-throughput data, Experiment
design, Expression analysis, ChIP-chip data analysis, ChIP-seq data analysis,
Data storage and management, Results and discussion, Summary of results,
Computational results, Biological results, Medical results, Additional results,
Discussion.
This note covers the
following topics: Molecular Biology, Molecular Biology Information - DNA,
Protein Sequence, Macromolecular Structure and Protein Structure Details, Gene
Expression Datasets, New Paradigm for Scientific Computing, General Types of
Informatics in Bioinformatics, Genome Sequence, Protein Sequence, Major
Application: Designing Drugs, Finding Homologues, Genome Characterization.
This note explains the
following topics: Modern approaches in Bioanalysis and Bioassays, Spectroscopic
techniques: UV-Visible spectroscopy, Fluorescence spectroscopy, IR spectroscopy,
CD spectroscopy, and Mass spectroscopy, Light Microscopy; Fluorescence
microscopy, Atomic force microscope, Electron microscope, Scanning electron
microscopy, Transmission Electron microsope, Application of microscope in
analyzing biological samples.
This note provides a hands-on approach to students in the
topics of bioinformatics and proteomics. Topics covered includes: sequence
analysis, microarray expression analysis, Bayesian methods, control theory,
scale-free networks, and biotechnology applications.
Author(s): Prof. Gil Alterovitz, Prof. Manolis Kellis and
Prof. Marco Ramoni